Reina Consorte de España Princesa de Napoles y de Silicias María Cristina Ferdinanda of Bourbon-Two Sicilies, Queen consort of Spain

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Maria Christina of the Two Sicilies (Italian: Maria Cristina Ferdinanda di Borbone, principessa delle Due Sicilie, Spanish: María Cristina de Borbón, princesa de las Dos Sicilias; 27 April 1806–22 August 1878) was Queen Consort of Spain (1829 to 1833) and Queen Regent of Spain (1833 to 1840).

The new government required the ex-regent to leave Spain. After an unsuccessful attempt to return to power, Maria Christina retired permanently to exile in France after 1844. France remained her primary residence for the remainder of her life.

A revolution forced daughter Isabella II from her throne on 30 September 1868 and she joined her mother in exile in France. Isabella II renounced the throne in favor of her son, Alfonso XII, on 25 June 1870. Supporters of Alfonso XII made it clear that neither his mother nor grandmother could play an active role in the effort to restore the monarchy. When Alfonso XII regained the Spanish crown on 29 December 1874, Maria Christina and Isabella II were permitted to return to Spain as visitors but denied permission to live there permanently. Neither was allowed to exercise influence in the Spanish government.

The marriage to Muñoz and the events of Maria Christina's turbulent regency drove a permanent wedge between her and her Spanish royal offspring. Neither Isabella II nor Alphonso XII had much interest in a relationship with the former Queen Regent.

Maria Christina died in Le Havre, France on 22 August 1878. As the widow of Ferdinand VII and the mother of Isabella II, Maria Christina was buried in the royal crypt of El Escorial monastery.