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Ann Dandridge Costin, who was one-quarter African, one-quarter Cherokee Indian, and half-white; there is further evidence of an illegitimate half-brother Ralph Dandridge (date of birth unrecovered), who was probably white.
Source: http://www.singletonfamily.org/getperson.php?personID=I49632
http://www.theusgenweb.org/dcgenweb/links/notable_african_american....