[Note: Reposted with links to each name and deleted original post]
One of the wives listed for Rabbi Menachem Manesh Chayot (the one named Wife R' Menachem Chayot (Chayes)) is also the half-sister of his father Meir Chayos. This would make her his aunt.
A union between a nephew and his aunt is forbidden by Jewish law - while it's nevertheless possible for that kind of union to happen anyways, it would be very unlikely for it to happen within a family of Rabbis. So most likely she was not the daughter of Shimshon Chayot or she was not the wife of this Rabbi Menachem Manesh Chayot.
What is the a source for this Wife R' Menachem Chayot (Chayes) being married to Rabbi Menachem Manesh Chayot?
What is the a source for this Wife R' Menachem Chayot (Chayes) being the daughter of Shimshon Chayot?
(As an aside, Rabbi Menachem Manesh Chayot was the great-grandson of Menahem Manish Chajes ABD Vilna, ABD Vilna, so he may very well have had many other second cousins with the same name)