Here is a Rabbi Kopel who is a great grand son of TaZ but it doesn't seem to match your other info (This is start of Wiesel family)
Chapter 2a – Descendants of TaZ’ son -
T2.3 Rabbi Shlomo
T2.3 Rabbi Shlomo ca. 1610 (1619?) - ca. 1664 married daughter of Rabbi Zalman of Kolomea.
Died with his brother in 1664 in an anti-Jewish riot in Lvov. The local Jesuit students made it a habit of attacking Jews in the streets. One day the Jews fought back. A terrible pogrom erupted on May 24, 1664 and the two brothers were killed. Their epitaph read:
Great G-d, ruler of all, avenge the blood of your servants, the bodies of the brothers, who were loved and cherished. One, who was like a lion, the great master, our teacher, Rabbi Mordechai and the second, the great and pious rabbi, our teacher, Rabbi Shlomo, the sons of the great Rabbi David … they studied Torah day and night. Therefore, avenge their blood…
T3.1 Michal {Yechiel Mechel} Wiesel-Segal of Ostraha b. ca. 1640 ca. 1645 - d. ca. 1670
T4.1 Rabbi David HaLevi Kopel b. ca. 1670 ca. 1690 (married Chaya, 1st cousin, daughter of his aunt, Bluma )
T5.1 Rabbi Michal {Yechiel Mechel} of Spinka b. 1750 d.1830 who adopted the surname Weisel. (According to the preserved traditions, Rabbi Shlomo’s son Michal had a son Rabbi David. Rabbi David had a son named R. Michal, after his grandfather. When Rabbi David suddenly died, leaving R. Michal orphaned at a young age, a match was arranged for eventual marriage by his mother. When Michal matured, he discovered a flaw in the family background of the bride to be and refused to marry her. When his prospective father-in-law threatened to expose R. Michal to the military draft, R. Michal fled to Nagiv, Hungary, where he earned a living as a teacher. He eventually acquired a good reputation as a scholar, married an upstanding woman and settled in Spinka. He was known as an “Ish Mofet”, a miracle worker, so pious that he fasted from Sabbath to Sabbath. )
T6.1 Rabbi Yaakov Avraham HaLevi Wiesel, also known as Rav Avram Wiesel of Bilvaretz, kabbalist (b. Statel near Krakow – d. 9 Kislev 1873. ) married Rechel ……
(Numerous descendants of Rabbi Avram Wiesel, who married into the Greensweig, Panath, Rosenberg, Rubin, Wagschal, Weiss and many other families, are documented in Asher Zelig Steinmetz, Ktav Sofer (Budapest: 1942), David Aviram, Hitchadshut (Haifa: 1993), Eliezer Pinchas Sofer, Seyfer di Sheyne Farangenheyt in Mamorosh (Brooklyn: Mamorosh Holocaust Memorial Fund, 1999) and Yosef Weiss, Sefer Beit Yosef Lahava (Bnei Brak: 2000).)